Basic shortcuts to smooth the use of Excel. CFO.com has a great article for us Excel users, ten shortcut tips. Here is one, click through for the rest:
Saving, Printing, Opening. If you spend a lot of time opening, closing, and printing spreadsheets – and who doesn’t – the F12 key could become your best friend. On its own, the F12 key will open up the "Save As" dialog box. But add the Shift key to it, and Excel will automatically save the current sheet. Type "Control" and F12 together and Excel will provide a fresh spreadsheet.